Animal Models of Diabetic Neuropathic Pain

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Animal models of diabetic neuropathic pain.

Diabetic neuropathy is a common complication of diabetes. It occurs in approximately 10-20% of patients with diabetes, or roughly 40-50% patients with diabetic neuropathy. However, the pathogenesis of diabetic neuropathic pain is still largely unknown. Several animal models have been used to study the underlying mechanisms for this complication. Some commonly used animal models include streptoz...

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Animal Models of Diabetic Neuropathic Pain

▼ Diabetic neuropathy is a common complication of diabetes. It occurs in approximately 10–20 % of patients with diabetes, or roughly 40–50 % patients with diabetic neuropathy. However, the pathogenesis of diabetic neuropathic pain is still largely unknown. Several animal models have been used to study the underlying mechanisms for this complication. Some commonly used animal models include stre...

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Animal Models of Diabetic Neuropathic Pain

▼ Diabetic neuropathy is a common complication of diabetes. It occurs in approximately 10–20 % of patients with diabetes, or roughly 40–50 % patients with diabetic neuropathy. However, the pathogenesis of diabetic neuropathic pain is still largely unknown. Several animal models have been used to study the underlying mechanisms for this complication. Some commonly used animal models include stre...

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Animal models of neuropathic pain.

Animal models are pivotal for understanding the mechanism of neuropathic pain and development of effective therapy for its optimal management. A battery of neuropathic pain models has been developed to simulate the clinical pain conditions with diverse etiology. The present review exhaustively discusses the methodology, behavioral alterations, limitations, and advantages of about 40 different a...

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Neuropathic Pain in Animal Models of Nervous System Autoimmune Diseases

Neuropathic pain is a frequent chronic presentation in autoimmune diseases of the nervous system, such as multiple sclerosis (MS) and Guillain-Barre syndrome (GBS), causing significant individual disablement and suffering. Animal models of experimental autoimmune encephalomyelitis (EAE) and experimental autoimmune neuritis (EAN) mimic many aspects of MS and GBS, respectively, and are well suite...

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ژورنال

عنوان ژورنال: Experimental and Clinical Endocrinology & Diabetes

سال: 2014

ISSN: 0947-7349,1439-3646

DOI: 10.1055/s-0033-1363234